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The combination of Purchase oxycodone online and other opioids demands careful monitoring to prevent harmful adverse consequences such as drowsiness or breathing difficulties as well as constipation and dependence.   This is how you can do this safely and maintain your health and quality of life 1.   Follow a Doctor-Guided Plan Do not take oxycodone or other opioids when your physician has prescribed them in combination.   Combining opioids increase the risk of getting sick which is why doses have to be carefully weighed.   Don't alter the dose of your medicine without medical advice. 2.   Do not mix with depressions. Don't mix opioids and alcohol with benzodiazepines or the benzodiazepines (e.g. or Xanax) and sleep aids, unless directed to do so.   They can cause a slowing of heart rate and breathing and can lead to an the overdose. 3.   Space Doses Properly If you are using both short-acting as well as long-acting opioids, adhere to the prescribed s...